Nitroglycerin is used for the treatment of angina, acute myocardial infarction, severe hypertension, and acute coronary artery spasms. [1][14] It may be administered intravenously, as a sublingual spray/tablet, or as a patch applied to the skin. What is nitroglycerin, and how does it work? Nitroglycerin is a medication that treats angina and anal fissures. It works by promoting blood flow. The body breaks nitroglycerin down into nitric. Nitroglycerin, a powerful explosive and an important ingredient of most forms of dynamite. It is also used with nitrocellulose in some propellants, especially for rockets and missiles, and medically it is employed as a vasodilator in the easing of cardiac pain. Nitro-Dur (Nitroglycerin) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Nitroglycerin, as well as the onset and duration of action of each form, is different. The sublingual or tablet spray of nitroglycerin has a two-minute onset and a twenty-five-minute duration of action. Find patient medical information for Nitroglycerin on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings What is nitroglycerin? Nitroglycerin is used in adults to treat or prevent attacks of chest pain (angina). Nitroglycerin may also be used for purposes not listed in this medication guide. Nitroglycerin is used to prevent angina (chest pain) caused by coronary artery disease. This medicine is also used to relieve an angina attack that is already occurring. Nitroglycerin belongs to the group of medicines called nitrates. This guide on nitroglycerin how to use covers everything you need to know. You will learn the Rule of 3, exact administration steps, when nitroglycerin is appropriate, when to call 911, and what to do about common side effects like that famous nitro headache. Easy-to-read patient tips for nitroglycerin covering how it works, benefits, risks, and best practices.